Background Inadequate knowledge among health care providers (HCPs) and parents of affected children limits the understanding and utility of secondary genetic findings (SFs) in under-represented populations in genomics research. SFs arise from deep DNA sequencing done for research or diagnostic purposes and may burden patients and their families despite their potential health importance. This study aims to evaluate the perspective of both groups regarding SFs and their choices in the return of results from genetic testing in the context of orofacial (...) clefts.Methods Using an online survey, we evaluated the experiences of 252 HCPs and 197 parents across participating cleft clinics in Ghana and Nigeria toward the return of SFs across several domains.Results Only 1.6% of the HCPs felt they had an expert understanding of when and how to incorporate genomic medicine into practice, while 50.0% agreed that all SFs should be returned to patients. About 95.4% of parents were willing to receive all the information from genetic testing (including SFs), while the majority cited physicians as their primary information source (64%).Conclusions Overall, parents and providers were aware that genetic testing could help in the clinical management of diseases. However, they cited a lack of knowledge about genomic medicine, uncertain clinical utility, and lack of available learning resources as barriers. The knowledge gained from this study will assist with developing guidelines and policies to guide providers on the return of SFs in sub-Saharan Africa and across the continent. (shrink)

Brendle, J., H. Judah and S. Shelah, Combinatorial properties of Hechler forcing, Annals of Pure and Applied Logic 59 185–199. Using a notion of rank for Hechler forcing we show: assuming ωV1 = ωL1, there is no real in V[d] which is eventually different from the reals in L[ d], where d is Hechler over V; adding one Hechler real makes the invariants on the left-hand side of Cichoń's diagram equal ω1 and those on the right-hand side equal 2ω (...) and produces a maximal almost disjoint family of subsets of ω of size ω1; there is no perfect set of random reals over V in V[ r][ d], where r is random over V and d Hechler over V[r], thus answering a question of the first and second authors. (shrink)

Business Ethics: A European Review, EarlyView.

In this work we give a complete answer as to the possible implications between some natural properties of Lebesgue measure and the Baire property. For this we prove general preservation theorems for forcing notions. Thus we answer a decade-old problem of J. Baumgartner and answer the last three open questions of the Kunen-Miller chart about measure and category. Explicitly, in \S1: (i) We prove that if we add a Laver real, then the old reals have outer measure one. (ii) We (...) prove a preservation theorem for countable-support forcing notions, and using this theorem we prove (iii) If we add ω 2 Laver reals, then the old reals have outer measure one. From this we obtain (iv) $\operatorname{Cons}(\mathrm{ZF}) \Rightarrow \operatorname{Cons}(\mathrm{ZFC} + \neg B(m) + \neg U(m) + U(c))$ . In \S2: (i) We prove a preservation theorem, for the finite support forcing notion, of the property " $F \subseteq ^\omega\omega$ is an unbounded family." (ii) We introduce a new forcing notion making the old reals a meager set but the old members of ω ω remain an unbounded family. Using this we prove (iii) $\operatorname{Cons}(\mathrm{ZF}) \Rightarrow \operatorname{Cons}(\mathrm{ZFC} + U(m) + \neg B(c) + \neg U(c) + C(c))$ . In \S3: (i) We prove a preservation theorem, for the finite support forcing notion, of a property which implies "the union of the old measure zero sets is not a measure zero set," and using this theorem we prove (ii) $\operatorname{Cons}(\mathrm{ZF}) \Rightarrow \operatorname{Cons}(\mathrm{ZFC} + \neg U(m) + C(m) + \neg C(c))$. (shrink)

'Johann Sommerville's is an impeccable textbook. Simply written, it provides exposition of Hobbes' arguments in the context of English and continental thought'. P. Springborg, University of Sydney, Political Studies, Vol. XL1, No 2 6/93 Thomas Hobbes was probably the greatest of British political theorists. Too often commentators have failed to grasp his meaning because they have ignored the historical context in which he wrote. Drawing on much recent scholarship and on many little-known seventeenth century sources, this book presents a (...) lucid and jargon-free examination of Hobbes' arguments, setting them against a background of the ideas of his contemporaries and of the political events of his lifetime. By viewing Hobbes in his context, the book both clarifies his theories and illuminates European thinking at a critical stage in the development of modern political ideas. (shrink)

Introduction , Sophie Gibb 1. Mental Causation , John Heil 2. Physical Realization without Preemption , Sydney Shoemaker 3. Mental Causation in the Physical World , Peter Menzies 4. Mental Causation: Ontology and Patterns of Variation , Paul Noordhof 5. Causation is Macroscopic but not Irreducible , David Papineau 6. Substance Causation, Powers, and Human Agency , E. J. Lowe 7. Agent Causation in a Neo-Aristotelian Metaphysics , Jonathan D. Jacobs and Timothy O’Connor 8. Mental Causation and Double Prevention (...) , Sophie Gibb 9. The Identity Theory as a Solution to the Exclusion Problem , David Robb 10. Continuant Causation, Fundamentality, and Freedom , Peter Simons 11. There is no Exclusion Problem , Steinvor Tholl Arnadottir and Tim Crane. (shrink)

This book outlines the realist and pluralist philosophy of John Anderson, Australia's most original thinker. His teaching at Sydney University and his arti6es have deeply influenced Australian intellectual life. Several main themes run through his work, but Anderson never gave an overall account of his views. This is remedied here: exhibiting the range of Anderson's thought from logic, epistemology and theory of mind, to language and social theory, this volume sketches realism as a systematic philosophical position, while showing something (...) of the history of ideas in Australia. (shrink)

This appeared in Philosophy and Phenomenological Research 59:473-93, as a response to four papers in a symposium on my book The Conscious Mind . Most of it should be comprehensible without having read the papers in question. This paper is for an audience of philosophers and so is relatively technical. It will probably also help to have read some of the book. The papers I’m responding to are: Chris Hill & Brian McLaughlin, There are fewer things in reality than are (...) dreamt of in Chalmers’ philosophy Brian Loar, David Chalmers’ The Conscious Mind Sydney Shoemaker, On David Chalmers’ The Conscious Mind Stephen Yablo, Concepts and consciousness Contents. (shrink)

On 5 August 1968, publication of the Harvard Committee’s report on the subject of “irreversible coma” established a standard for diagnosing death on neurological grounds. On the same day, the 22nd World Medical Assembly met in Sydney, Australia, and announced the Declaration of Sydney, a pronouncement on death, which is less often quoted because it was overshadowed by the impact of the Harvard Report. To put those events into present-day perspective, the authors reviewed all papers published on this (...) subject and the World Medical Association web page and documents, and corresponded with Dr A G Romualdez, the son of Dr A Z Romualdez. There was vast neurological expertise among some of the Harvard Committee members, leading to a comprehensible and practical clinical description of the brain death syndrome and the way to diagnose it. This landmark account had a global medical and social impact on the issue of human death, which simultaneously lessened reception of the Declaration of Sydney. Nonetheless, the Declaration of Sydney faced the main conceptual and philosophical issues on human death in a bold and forthright manner. This statement differentiated the meaning of death at the cellular and tissue levels from the death of the person. This was a pioneering view on the discussion of human death, published as early as in 1968, that should be recognised by current and future generations. (shrink)

How are permutation arguments for the inscrutability of reference to be formulated in the context of a Davidsonian truth-theoretic semantics? Davidson takes these arguments to establish that there are no grounds for favouring a reference scheme that assigns London to “Londres”, rather than one that assigns Sydney to that name. We shall see, however, that it is far from clear whether permutation arguments work when set out in the context of the kind of truth-theoretic semantics which Davidson favours. The (...) principle required to make the argument work allows us to resurrect Foster problems against the Davidsonian position. The Foster problems and the permutation inscrutability problems stand or fall together: they are one puzzle, not two. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:"And They Sang A New Song":Reading John's Revelation From The Position Of The LambJ.A. Jackson (bio) and Allen H. Redmon (bio)Then one of the elders said to me, "Do not weep. See, the Lion of the tribe of Judah, the Root of David, has conquered, so that he can open the scroll and the seven seals." Then I saw between the throne and the four living creatures and (...) among the elders a Lamb standing as if it had been slaughtered.—Revelation 5:5–6In an interview with Markus Müller, René Girard asserts the importance of taking into account the apocalypticism of Christianity. Apocalypse, Girard reminds us, "means revelation: apocalypto means to open up and to show the truth. But it also means absolute violence, so the apocalypse is a violent revelation and a revelation of violence" (Girard 1996). That the Revelation is a violent revelation has been well established. Despite textual evidence that would beg those who approach the text to do just the opposite, readers have fixated on the violence of the Revelation since its inception, finding in it God's final retribution against those who persecute the Church.1 Commentators such as Dennis E. Johnson, William Hendricksen, and George Elden Ladd have produced recent, full-length commentaries that champion the appearance of a Christ in Revelation ready to establish himself as a military champion and exact his revenge on those who persecute him (see, for example, Johnson 2001; Hendricksen 1998; and Ladd 1993). These accounts, and those that follow suit, are blinded by the violent revelation of John's apocalyptic narrative and fail to see the poem's revelation of violence—the other, prophetic half of what Girard rightly contends exists in Christian apocalypse.This error is understandable to some extent. Read in its own light and apart from the Gospel revelation as understood by those familiar with mimetic [End Page 99] theory, one has no hermeneutical principle for recognizing the end to which John is writing. The victims of the text can be ignored in the precise way that all victims are disregarded when the scapegoat mechanism functions properly. Such should not be the case in the Revelation, though, a text in which the scapegoat mechanism is exposed and pushed to its logical conclusions. John offers his reader a glimpse into the way this mechanism will function when all that is left is wall-to-wall violence, when one is left with only two alternatives: succumb to the mechanism and reciprocate its violence, or extricate oneself through nonreciprocation (and potentially die).In the margins of the violent revelation in John's apocalyptic vision, a revelation of violence emerges that can expose humankind's potential to annihilate itself and the mechanism with which it will do so. When read through the lens of mimetic theory, one discovers that John's narrative delivers a revelation of violence, an explicit naming and unmasking of the sacrificial mechanism that can capture for the reader not only the machinations of the sacrificial apparatus but one's own potential participation in it as well. As such, the poem can posit itself as a commandment (a Thou-shall-not-murder) that ultimately refuses the temptation to respond to violence in violence.The fact that John uses the apocalyptic to present this directive should not be surprising. Girard writes: "Only through the mediation of the scapegoat mechanism can violence become its own remedy, and the victimage mechanism can only be triggered by the frenetic paroxysm of the 'crisis.' This means that the violence, having lost its vitality and bite, will paradoxically be more terrible than before its decline. As the whole of humanity makes the vain effort to reinstate its reconciliatory and sacrificial virtues, this violence will without doubt tend to multiply its victims, just as happened in the time of the prophets" (Girard 1978, 195–96). While Girard's commentary on biblical eschatology and apocalypse refers mainly to the scapegoat mechanism as it applies to and is revealed in the Gospel texts, we see the immediacy and the frenzy of the apocalyptic and the ubiquitous violent mimetic appropriations also performed in John's Revelation.2 John captures... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Royce, Racism, and the Colonial IdealWhite Supremacy and the Illusion of Civilization in Josiah Royce's Account of the White Man's Burden1Tommy J. CurryNo colony can be made by a theory of Imperialism, it can only be made by people who want to colonize and are capable of maintaining themselves as colonists.—Sir Sydney OlivierIntroductionAs with most historic white figures in philosophy, their repopularization and reintroduction into contemporary circles commits (...) their work, regardless of its initial silence, to speak to the problem of anti-Black racism in America. Josiah Royce is no different in this regard. In recent years, white scholars like Jacquelyn Kegley and Shannon Sullivan have introduced revisions to Royce's thought that make it appear multicultural and antiracist, despite the anachronism of such a contention. According to Kegley, "Royce believes, as others in the contemporary scene, that 'race' as a concept cannot be eliminated, [because] it plays too crucial a role, both positive and negative, in self- and social identification" (216). While Kegley is correct that contemporary scholars like Lucius Outlaw and Cornel West have adamantly defended the importance of race as a social and cultural entity, her claim is in stark contradiction to the racial eliminativism of other scholars like Anthony Appiah and Alain Locke, whom she also contends that Royce agrees with simultaneously.2 While it makes perfect sense for Kegley to try to put Royce in conversation with contemporary Black thinkers in race theory, her work is indicative of a trend aiming to gain currency for historic white thinkers in current race debates at the expense of historical accuracy. Black scholars who studied under Royce and applied his theories to the race problem from the mid-1900s onward, like William H. Ferris3 and William T. Fontaine,4 are ignored by white scholars because the first application of Roycean philosophy supported assimilationism. It is only today with the political and ideological [End Page 10] ethicizations of racial diversity and multiculturalism that Royce's work is interpreted as critically conserving race.5In contrast to contemporary works on Royce and race, this article seeks to evaluate the current claims for the relevance of Royce's views in contemporary debates on race. I maintain that only by taking Royce out of his historical context (late nineteenth-and early twentieth-century thought) do his ideas on race acquire a level of importance that cannot be supported by the actual evidence he himself advances. Conversely, by actually placing Royce in his historical context, this article will demonstrate that Royce's 1905 article entitled "Race Questions" (later published as "Race Questions and Prejudices" in 1906) is an unapologetic extension of his 1900 article entitled "Characteristic Tendencies of American Civilization," where Royce adamantly champions British colonialism and assimilation as the remedy to the burgeoning race problem both at home and abroad. I begin with a critical analysis that places Josiah Royce's attitudes firmly within the boundaries of his times. In what follows, I will attempt to contextualize Royce's seemingly progressive stance on Japan as part of a more general reaction whites had during the early 1900s to Russia's defeat by the Japanese. Instead of reading Royce's stance on Japan as a moment of exceptionalism, I contend that Royce's attitude was in fact a popular disposition that signaled the inevitable shift of race science away from biological determinism toward more environmentalist explanations. Secondly, and perhaps more importantly, I will show that Royce's disposition toward Blacks was firmly rooted in a colonial and assimilationist logic that ultimately sought the cultural destruction of African-descended people. A closer look at Royce's prefatory remarks on British colonialism from 1900 and his valorization of English colonial administration in Jamaica actually reveals an insidious racial dynamic in Royce's thought that is anything but antiracist. Finally, having established Royce's philosophical stake in American assimilation and Western domination, I argue that the "provincial revision" currently in vogue amongst American philosophers working with Royce is simply not enough to overturn Royce's clearly racist investments in dealing with the race question.If I Can Think It... Then I Can Do It—Reading Royce... (shrink)

Originally published in 1937 on the occasion of the five hundredth anniversary of the birth of Isaac ben Judah Abravanel, this book contains six essays on his teaching and thought by a number of scholars. The authors explain key points such as the Iberian background to Abravanel's work, his differences with other philosophers of his age, and the influence of his son, Leone Ebreo, on the Renaissance. This book will be of value to anyone with an interest in Abravanel's (...) life and teaching or in Medieval Jewish philosophy. (shrink)

Although the Psalms may have originated primarily within the liturgical life of ancient Israel and Judah, they were nonetheless appropriated, preserved, and transmitted as instruction for the faithful.